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Advancing programmable gene expression in plants using CRISPRi-based Boolean gates
To advance the toolset for controlling plant gene expression, we developed a CRISPR interference-based platform for the construction of synthetic Boolean logic gates that is functional in multiple plant species. These genetic circuits are programmable and reversible in nature, which will enable spatiotemporal control of plant responses to dynamic cues.
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What’s next for molecular diagnostics and precision medicine?
Learn about the fast-moving advances in molecular diagnostics and precision medicine from our profiling companies and landscape feature.
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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
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Identification of mobile genetic elements with geNomad
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Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method
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Linking CRISPR–Cas9 double-strand break profiles to gene editing precision with BreakTag